!!

Powering down the Pfam website
On October 5th, we will start redirecting the traffic from Pfam (pfam.xfam.org) to InterPro (www.ebi.ac.uk/interpro). The Pfam website will be available at legacy.pfam.xfam.org until January 2023, when it will be decommissioned. You can read more about the sunset period in our blog post.

Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PPAC_THEMA (Q9WZ56)

Summary

This is the summary of UniProt entry PPAC_THEMA (Q9WZ56).

Description: Probable manganese-dependent inorganic pyrophosphatase EC=3.6.1.1
Source organism: Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (NCBI taxonomy ID 243274)
Length: 548 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
Pfam DHH 6 383
Pfam CBS 73 128
Pfam DRTGG 144 247
Pfam CBS 250 305
Pfam DHHA2 419 543

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9WZ56. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MKALERVYVI GHKNPDTDSV CSAIGYAHFK NNVEKGKTFI PARSGDLTNE
50
51
SLFVLKYFGM NPPLHIETLE PTVEDLELKN PIFVTPDTSA YDVAMLMESR
100
101
GIKNVPVVSK EKMIGVVTES NIARVYVRRL KIEPLVIHPV PFDQLVRILK
150
151
AEVVCDYMKE KTVSGKVHIA VDALHVLLGK IEIGDVVIVG DNEPAQIALL
200
201
EKGAKLMIVV NNAPVSNRVL EIAKEKNAAV LRVKFDAFSA AKLINLSLPV
250
251
TLVMSKKFPT VTKKDTLEEV KEIVFTSKIR AAFVEDEKGR LCGVITRTDL
300
301
LKDVRKKVIL VDHNEITQAP EGVEKAEILE IIDHHRLGGL STLNPVFFYN
350
351
EPVGSTSTIV AEFFLKNGVK MEREIAGILL SGIVSDTLFF KLSTTTEKDR
400
401
KMANFLADVA KLDLEKFAKK LLKEGMKIPE DVDPAELLKR DVKVYEMGEE
450
451
SFAVSQIMTS DFSTLLKEKE RFMNTLKTLK GEFGVKHFFV LFTNPVEEAS
500
501
LLMMDGDQKL VEKAFNAEKK DGLFLLKGVM SRKKDFVPKI GEVLRRER  
548
 

Show the unformatted sequence.

Checksums:
CRC64:D1CF282F70EA56DE
MD5:7b4c42e908fc0eced8d50cffb4ecf009

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;