!!

Powering down the Pfam website
On October 5th, we will start redirecting the traffic from Pfam (pfam.xfam.org) to InterPro (www.ebi.ac.uk/interpro). The Pfam website will be available at legacy.pfam.xfam.org until January 2023, when it will be decommissioned. You can read more about the sunset period in our blog post.

Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PADI1_MOUSE (Q9Z185)

Summary

This is the summary of UniProt entry PADI1_MOUSE (Q9Z185).

Description: Protein-arginine deiminase type-1
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
Length: 662 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
Pfam PAD_N 1 113
low_complexity n/a 71 83
Pfam PAD_M 115 272
disorder n/a 126 127
disorder n/a 132 137
low_complexity n/a 261 271
Pfam PAD 280 659

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9Z185. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MASPRAVQLS LRKPTHAVCV VGVETLVNVY SDVPKGAKTF GVSGSSEVKI
50
51
YMVYDPSRVA EPAGWAHWPL DANVDVVVVA DTVSKDLYDF KVKVSYFESQ
100
101
EAAALAHSVL YLTAVDVSLD VDTGRTGKVK KGSGDKKTWR WGPGGSGAIL
150
151
LVNCDRDIHG SREDLHANHL KSLEDLQDMS PMVLSCGGPD ELFESHKLVL
200
201
KASLSDSRRL KVFCARGGTS LSNYKQVLGP RHSSYEVERH SGERAIQFYV
250
251
EGLAFPDASF SGLLSLSVSL VDTRPLSEVS VFTDSVTFRV APWIMTPNTQ
300
301
PPLELYVCSV TDIHGRNDKF LEDMSHLATK ANCKLVVCPR AENRNDRWIQ
350
351
DELEFGYIDA PHKSFPVVFD SPRNRGLRDF ALKRILGPDF GYVTREIEFA
400
401
GASGLDSFGN LDVSPPVRVG NTDYPLGRIL IGGSFPKPSG RRMARVVRDF
450
451
LQAQQVQSPV ELYSDWLSVG HVDEFLSFVP TSDQKGFRLL LASPSACLQL
500
501
FQEKKEEGYG EAEQFDGLKH KAKRSINDIL ADKHLRRDSA HVQKCIDWNR
550
551
EVLKRELGLS ESDIVDIPQL FFLKGAYAEA FFPDMVNMVV LGKYLGIPKP
600
601
FGPLINGRCC LEEKVRSLLE PLGLRCVFID DFLFYHQLLG EIHCGTNVRR
650
651
KPFTFKWWNS VP                                         
662
 

Show the unformatted sequence.

Checksums:
CRC64:F9A6C7DFF1031D8A
MD5:4ef2be10b801d61f2ae6319d1bd86396

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;